A genetically encoded inhibitor of 53BP1 to stimulate homology-based gene editing

نویسندگان

  • Marella D. Canny
  • Leo C.K. Wan
  • Amélie Fradet-Turcotte
  • Alexandre Orthwein
  • Nathalie Moatti
  • Yu-Chi Juang
  • Wei Zhang
  • Sylvie M. Noordermeer
  • Marcus D. Wilson
  • Andrew Vorobyov
  • Meagan Munro
  • Andreas Ernst
  • Michal Zimmermann
  • Timothy F. Ng
  • Sachdev S. Sidhu
  • Frank Sicheri
  • Daniel Durocher
چکیده

The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON, M5G 1X5, Canada Department of Molecular Genetics, University of Toronto, ON, M5S 3E1, Canada. Present address: St-Patrick Research Group in Basic Oncology, Université Laval Cancer Research Center, and Oncology Axis-CHU de Québec Research Center – Université Laval, Quebec City, QC, G1R 2J6, Canada Present address: Department of Oncology, McGill University, Montreal, QC, H3G 0G4, Canada and Segal Cancer Center, Jewish General Hospital, Lady Davis Institute for Medical Research, Montreal, QC, H3T 1E2, Canada The Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Research, University of Toronto, ON, M5S 3E1, Canada Present address: Institute of Biochemistry II, Goethe University School of Medicine, TheodorStern-Kai 7, 60590, Frankfurt am Main, Germany.

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تاریخ انتشار 2016